IBS/SIBO Research Update – 2021
Video course: 3.0 credit hours (general) from NANCEAC
NANCEAC is ND certification for all US States and Canadian Provinces. Learn more about this certification here.
2020-2021 was a MASSIVELY important year in terms of clinically relevant research on IBS and SIBO. Get updated!
This CEU course is a review and critical appraisal of recent clinically relevant research in approaches to IBS/SIBO. The studies we specifically critically review are below:
- Pimentel, Mark, Richard J. Saad, Millie D. Long, and Satish S.C. Rao. 2020. “ACG Clinical Guideline: Small Intestinal Bacterial Overgrowth.” The American Journal of Gastroenterology 115 (2): 165–78.
- Villanueva-Millán, María & Sanchez, Maritza & Morales, Walter & Leite, Gabriela & Weitsman, Stacy & Parodi, Gonzalo & Celly, Shreya & Do, Huongly & Pimentel, Maya & Fowler, Halley & Cohrs, Daniel & Mathur, Ruchi & Pimentel, Mark & Rezaie, Ali. (2021). Sa615 Transplantation of fusobacterium varium in vivo results in an increase of pro-inflammatory cytokines and stool wet weight. Gastroenterology. 160. S-574. 10.1016/S0016-5085(21)02071-0.
- Pimentel, Mark & Hosseini, Ava & Chang, Christine & Mathur, Ruchi & Rashid, Mohamad & Sedighi, Rashin & Fowler, Halley & Torosyan, John & Wang, Jiajing & Rezaie, Ali. (2021). Fr248 Exhaled hydrogen sulfide is increased in patients with diarrhea: results of a novel collection and breath testing device. Gastroenterology. 160. S-278.
- Leite, Gabriela, Walter Morales, Stacy Weitsman, Shreya Celly, Gonzalo Parodi, Ruchi Mathur, Gillian M. Barlow, et al. 2020. “The Duodenal Microbiome Is Altered in Small Intestinal Bacterial Overgrowth.” PLoS ONE 15 (7 July): 1–17. https://doi.org/10.1371/journal.pone.0234906.
- Erdrich S, Tan ECK, Hawrelak JA, Myers SP, Harnett JE. Hydrogen-methane breath testing results influenced by oral hygiene. Sci Rep. 2021 Jan 8;11(1):26. doi: 10.1038/s41598-020-79554-x. PMID: 33420116; PMCID: PMC7794545.
- Lacy BE, Pimentel M, Brenner DM, Chey WD, Keefer LA, Long MD, et al. ACG Clinical Guideline: Management of Irritable Bowel Syndrome. Am J Gastroenterol. 2021 Jan 1;116(1):17–44.
- Krouwel M, Farley A, Greenfield S, Ismail T, Jolly K. Systematic review, meta-analysis with subgroup analysis of hypnotherapy for irritable bowel syndrome, effect of intervention characteristics. Complement Ther Med. 2021 Jan 27;57:102672.
- Goldenberg, Joshua Z., Lesley Ward, Andrew Day, and Kieran Cooley. 2018. “Naturopathic Approaches to Irritable Bowel Syndrome—A Delphi Study.” The Journal of Alternative and Complementary Medicine, September, acm.2018.0255.
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Learning Objectives
- Implement the 2020 ACG Guidelines as it relates to breath testing for patients with IBS
- Implement the 2020 ACG Guidelines as it relates to breath testing for patients taking PPIs
- Discriminate between normal and abnormal ppm of H2S on a breath test
- Contrast between the microbial diversity of the small intestine in those with and without SIBO
- Identify the aberrant organism most associated with SIBO in the REIMAGINE study
- Implement the 2020 ACG Guidelines as it relates to testing IBS patients for food sensitivities
- Implement the 2020 ACG Guidelines as it relates to the use of low FODMAP diets in IBS patients
- Select the Gut Directed Hypnotherapy regimen associated with the largest effect size
- Explain the need for GRADE within the context of Guideline development
- Critique a guideline using the AGREE-II criteria
- Define the concepts of pre- and post-test probability
- Calculate a post-test probability
